surest thing. that means by definition, the stuff that i'm used to. that i expect. that is an incremental gain. but this risky one, down at the bottom of the pile, well that could be great, but i'm just not sure. it's so new, it's so different, i'm not going to fund it. >> reporter: the sequester would have a similar effect on a wide range of programs across the country, from science, to public safety, to education. defense spending would take a huge hit with about $500 billion in cuts over the next ten years. in phoenix, mayor greg stanton calls sequestration the number one threat to his city's economy and disastrous for arizona jobs. >> in arizona, we would lose almost 50,000 jobs immediately. and we know that they're the right kind of jobs. 35,000 of those jobs would be in the defense and aerospace industries and in arizona, those are some of our highest paying jobs. >> reporter: that's the case in regions across the country where the defense industry is strong. one of those is johnstown, pennsylvania.